Development of the capacity for hepatic biotransformation of potentially toxic, endogenous compounds such as lithocholate may be dependent on induction by substrate or hormonal modulation.Our aim was to observe the ontogeny of hepatic sulfotransferase (ST) activity, a presumed detoxification pathway, and to determine the effect of substrate ingesti
Background: Doxorubicin (DOX) is one of the most effective chemotherapeutics for canine high-grade lymphoma.In addition to dose-dependent chronic cardiotoxicity, DOX can trigger acute cardiac arrhythmias during drug infusion.Diphenhydramine premedication is commonly used, as histamine release is a proposed mechanism for DOX-associated arrhythmogene
The most common method of strengthening columns is confining them with FRP composites, which increases their ultimate axial and lateral load capacity.The main objective of this research is to investigate square and rectangular RC columns strengthened with FRP composites.For this purpose, an existing laboratory sample was initially modeled in Abaqus